Figure 1
From: Cellular senescence induced by aberrant MAD2 levels impacts on paclitaxel responsiveness in vitro
siRNA MAD2 protein down-regulation in MCF-7 breast cancer cells. Western blot analysis demonstrates a robust reduction of the MAD2 protein in the MAD2↓ cells (lane 3) compared with the untransfected (lane 1) and scramble (lane 2) controls. β-actin was used as a loading control.
