Table 2 Efficacy results: objective response rates by WHO criteria and secondary tumour resection (intention-to-treat analysis)

From: Chemoradiotherapy with concurrent gemcitabine and cisplatin with or without sequential chemotherapy with gemcitabine/cisplatin vs chemoradiotherapy with concurrent 5-fluorouracil in patients with locally advanced pancreatic cancer – a multi-centre randomised phase II study

 

RT-5-FU ( n =31)

RT-GC ( n =32)

RT-GC+GC ( n =31)

 

No. (%)

No. (%)

No. (%)

Response

   

 Complete response

0 (0)

2 (6)

0 (0)

 Partial response

6 (19)

5 (16)

4 (13)

 Stable disease

5 (16)

11 (34)

10 (32)

 Disease control ratea

11 (35)

18 (56)

14 (45)

 Progressive disease

12 (39)

9 (28)

6 (19)

 Not assessable

8 (26)

5 (16)

11 (35)

Secondary resection

   

 Yes

4 (13)

8 (25)

6 (19)

 No

27 (87)

24 (75)

25 (81)

  1. Abbreviations: 5-FU=5-fluorouracil; C=cisplatin; G=gemcitabine; RT=radiotherapy.
  2. aDisease control rate=rate of complete response+partial response+stable disease.
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