Table 1 Phase I dose escalation
From: Phase I/II study of sequential therapy with irinotecan and S-1 for metastatic colorectal cancer
Dosage level | CPT-11 (mg m−2) | TS-1 (mg m−2) | No. of enroled patients |
|---|---|---|---|
0 | 75 | 80 | 0 |
1 | 100 | 80 | 3 |
2 | 125 | 80 | 6 |
3 | 150 | 80 | 3 |
From: Phase I/II study of sequential therapy with irinotecan and S-1 for metastatic colorectal cancer
Dosage level | CPT-11 (mg m−2) | TS-1 (mg m−2) | No. of enroled patients |
|---|---|---|---|
0 | 75 | 80 | 0 |
1 | 100 | 80 | 3 |
2 | 125 | 80 | 6 |
3 | 150 | 80 | 3 |
