Table 5 Overall response
From: Phase I/II study of sequential therapy with irinotecan and S-1 for metastatic colorectal cancer
No. of patients | CR | PR | SD | PD | NE | Response rate (%) | |
|---|---|---|---|---|---|---|---|
Phase I | |||||||
Overall | 12 | 1 | 4 | 4 | 2 | 1 | 41.7 |
Level | |||||||
1 | 3 | 0 | 1 | 1 | 1 | 0 | 33.3 |
2 | 6 | 0 | 2 | 2 | 1 | 1 | 33.3 |
3 | 3 | 1 | 1 | 1 | 0 | 0 | 66.7 |
Phase II | |||||||
Overall | 36 | 4 | 16 | 6 | 6 | 4 | 55.6 |
Prior chemotherapy | |||||||
No | 31 | 4 | 14 | 5 | 4 | 4 | 58.1 |
YES | 5 | 0 | 2 | 1 | 2 | 0 | 40 |
