Table 2 Characteristics of sequenced individuals

From: Absence of truncating BRIP1 mutations in chromosome 17q-linked hereditary prostate cancer families

 

N (%) or median (interquartile range)

Sex

 

 Male – PCa cases

88 (94)

 Female – BrCa cases

6 (6)

BrCa cases

 

 Age at diagnosis

61.5 (50.25–63.75)

PCa cases

 

 Age at diagnosis

55.5 (50–60)

 Pre-diagnosis PSA (ng ml−1)

6.15 (3.83–9.38)

 Surgery (% yes)

69 (78.4)

 Gleason scoresa

 

<7

39 (47)

7

39( 47)

>7

5 (6)

Stage a, b

 

 Localised

63 (78)

 Locally advanced

14 (17)

 Metastatic

4 (5)

  1. Abbreviations: BrCa=breast cancer; PCa=prostate cancer; PSA=prostate-specific antigen.
  2. a Columns do not add up to 88 due to missing data.
  3. b Localised=T1 or T2, N0 and M0 or Pre-Dx PSA <20 ng ml−1; locally advanced=T3 or T4, N0 and M0 or Pre-Dx PSA >20 ng ml−1 but <100 ng ml−1; metastatic=N1 or M1 or Pre-Dx PSA >100 ng ml−1.
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