Figure 1

31P-MR spectra showing the effect of the HDAC inhibitor LAQ824 on tumour cell metabolism in vitro (A) and in vivo (B). Metabolites: PC, phosphocholine; GPC, glycerophosphocholine; GPE, glycerophosphoethanolamine; Pi, inorganic phosphate; PMEs, phosphomonoesters; PDEs, phosphodiesters; PCr, phosphocreatine; NTPs, nucleotide triphosphates.