Table 1 Clinicopathological characteristics of the HNSCC population

From: Pemphigus vulgaris antigen mRNA quantification for the staging of sentinel lymph nodes in head and neck cancer

Patient no.

Age (years)

Gender

Tumour location

cTNM

No. SLN

SLN location a

Histopathology of SLN b

Bilateral neck dissection

No. of non-SLN (neck dissection)

Final pN stage c

1

29

M

OT

T2N0M0

4

IB, IIA

MI

No

29

pN1

2

58

M

OT

T1N0M0

3

III

MA

No

25

pN1

3

51

M

OC

T1N0M0

7

IB, II A, III

MI

Yes

27

pN1

4

53

M

OT

T2N0M0

5

IB, IIA, III

0

Yes

29

pN0

5

37

M

OT

T2N0M0

3

IB, IIA, IV

MA

No

18

pN1

6

44

M

OC

T2N0M0

4

IA,IB, III

MA

Yes

84

pN2bR+

7

55

M

OC

T2N0M0

3

IB, III

ITC

Yes

36

pN0

8

47

F

OT

T1N0M0

1

III

ITC

No

16

pN0

9

59

M

OP

T2N0M0

2

III

0

No

21

pN0

10

61

M

OC

T2N0M0

3

IB, IIA

0

Yes

40

pN0

11

57

M

OC

T1N0M0

5

IB, IIA, III, IV

0

Yes

36

pN0

12

31

F

OC

T2N0M0

4

IIA, IV

ITC

No

17

pN0

13

66

M

OT

T1N0M0

3

IB, IIA, III

ITC

No

17

pN0

14

49

F

OT

T2N0M0

3

III

0

Yes

8

pN0

15

79

M

OP

T1N0M0

4

IIA

0

No

3

pN0

16

75

F

OP

T2N0M0

4

II A,III

0

No

5

pN0

17

62

M

OT

T2N0M0

2

III

0

No

22

pN0

18

60

F

OC

T1N0M0

5

IA, IB, IV

0

Yes

13

pN0

19

61

M

OC

T2N0M0

3

IA, III

MI

Yes

44

pN2b

20

59

F

OP

T2N0M0

2

IIA, IIB

ITC

No

13

pN0

21

56

F

OP

T1N0M0

4

II A,III

0

No

17

pN0

22

49

M

OC

T1N0M0

4

IB, IIA, V

ITC

Yes

22

pN0

  1. Abbreviations: cTNM=clinical tumour node-metastasis stage; FOM=floor of mouth; HNSCC=head and neck squamous cell carcinoma; ITC=isolated tumour cell; MA=macrometastasis; MI=micrometastasis; OP=oropharynx; OT=oral tongue; SLN=sentinel lymph node; SR=sex ratio; m=mean; T=total.
  2. a Cervical lymph node levels according to Robbins et al (2002).
  3. b Pathological examination of the SLN by serial step sectioning and immunohistochemistry according to the classification of Hermanek (6).
  4. c pN stage was established according to the SLN and non-SLN status. The presence of isolated tumour cells was not taken into account in determining the final pN stage. No false negative cases were noted (pN+ with negative SLN)