Table 2 RT–PCR marker analysis according to lymph node staging (n=78) or patient staging (n=22)

From: Pemphigus vulgaris antigen mRNA quantification for the staging of sentinel lymph nodes in head and neck cancer

 

SLN histological staging

Patient staging

 

Negative node ( n =57)

ITC ( n =12)

MI ( n =5)

MA ( n =4)

SLN− ( n =16)

SLN+ ( n =6)

CK17

      

 Negative

9 (15.8%)

2 (16.6%)

0 (0%)

0 (0%)

13 (81%)

0 (0%)

 Positive

48 (84.2%)

10 (83.3%)

5 (100%)

4 (100%)

3 (19%)

6 (100%)

SSCA

      

 Negative

36 (63.1%)

6 (50%)

0 (0%)

0 (0%)

15 (94%)

0 (0%)

 Positive

21 (36.8%)

6 (50%)

5 (100%)

4 (100%)

1 (6%)

6 (100%)

PVA

      

 Negative

57/57 (100%)

12/12 (100%)

0 (0%)

0 (0%)

16 (100%)

0 (0%)

 Positive

0 (0%)

0 (0%)

5 (100%)

4 (100%)

0 (0%)

6 (100%)

  1. Abbreviations: CK17=cytokeratin 17; ITC=isolated tumour cell; MA=macrometastasis; MI=micrometastasis; RT–PCR=reverse transcriptase-PCR; SLN=sentinel lymph node; PVA=Pemphigus vulgaris antigen; SSCA=Squamous cell carcinoma antigen.