Table 3 ALDH1 expression and associations with basal markers, molecular subtypes, BMI-1, c-kit and p63 expression
Variable | ALDH1 negative ( n; %); n =95 | ALDH1 positive ( n; %); n =88 | OR (95% CI) | P -value |
|---|---|---|---|---|
CK 5/6 | ||||
 Negative | 86 (56) | 68 (44) | 1.0 |  |
 Positive | 8 (29) | 20 (71) | 3.2 (1.3–7.6) | 0.008 |
P-cadherin | ||||
 Negative | 75 (56) | 58 (44) | 1.0 |  |
 Positive | 20 (40) | 30 (60) | 1.9 (1.0–3.8) | 0.048 |
EGFR | ||||
 Negative | 81 (56) | 64 (44) | 1.0 |  |
 Positive | 12 (33) | 24 (67) | 2.5 (1.1–5.4) | 0.015 |
BLP1 | ||||
 Absent | 86 (56) | 69 (44) | 1.0 |  |
 Present | 8 (30) | 19 (70) | 2.9 (1.2–7.4) | 0.013 |
BLP2 | ||||
 Absent | 80 (56) | 62 (44) | 1.0 |  |
 Present | 15 (37) | 26 (63) | 2.2 (1.1–4.6) | 0.026 |
BLP3 | ||||
 Absent | 84 (56) | 67 (44) | 1.0 |  |
 Present | 10 (32) | 21 (68) | 2.6 (1.2–6.0) | 0.018 |
BLP4 (CBP) | ||||
 Absent | 80 (57) | 61 (43) | 1 |  |
 Present | 14 (34) | 27 (66) | 2.5 (1.2–5.2) | 0.011 |
BLP5 | ||||
 Absent | 77 (58) | 56 (42) | 1.0 |  |
 Present | 17 (35) | 32 (65) | 2.6 (1.3–5.1) | 0.005 |
TNP | ||||
 No | 65 (61) | 41 (39) | 1.0 |  |
 Yes | 30 (39) | 47 (61) | 2.5 (1.4–4.5) | 0.003 |
Molecular subtype | ||||
 Luminal | 56 (68) | 27 (32) | 1.0 |  |
 HER2 | 8 (36) | 14 (64) | 3.6 (1.4–9.7) | 0.008 |
 Basal-like | 14 (34) | 27 (66) | 4.0 (1.8–8.8) | 0.000 |
 Unclassified | 16 (44) | 20 (56) | 2.6 (1.2–5.8) | 0.018 |
c-kit | ||||
 Negative | 91 (52) | 84 (48) | 1.0 |  |
 Positive | 4 (50) | 4 (50) | 1.1 (0.3–4.4) | NS |
p63 | ||||
 Negative | 80 (53) | 71 (47) | 1.0 |  |
 Positive | 15 (47) | 17 (53) | 1.3 (0.6–2.7) | NS |
BMI-1 | ||||
 Negative | 64 (46) | 74 (54) | 1.0 |  |
 Positive | 31 (69) | 14 (31) | 0.4 (0.2–0.8) | 0.009 |
