Figure 1
From: C20orf20 (MRG-binding protein) as a potential therapeutic target for colorectal cancer
MRGBP is overexpressed in human colorectal tumours. (A) Relative expression of MRGBP in 15 additional colorectal tumours and the corresponding non-cancerous mucosa was analysed by real-time PCR. Quantity of MRGBP was normalised to HPRT1 expression. The y axis indicates the ratio of mean of MRGBP expression in tumour to that in normal tissues. The data represents mean±s.d. from three independent experiments. (B) Representative western blotting result of MRGBP in normal and tumour tissues from human colon. Expression of β-actin served as a control. (C) Multiple-tissue northern blot analysis of MRGBP in a panel of 23 normal human adult tissues. Expression of β- actin served as a control. (D) Representative images of immunohistochemical staining of MRGBP in normal and tumour tissues from human colon. Magnification: × 100.
