Table 1 Mean GI50 values (nM)±s.d. (n=3) for pemetrexed in mesothelioma cell lines grown in medium containing foetal bovine serum (FBS) or dialysed FBS (DFBS)
Cell line | MSTO | H28 | H226 | D2052 | D2452 | JL1 | DM3 | RS5 |
|---|---|---|---|---|---|---|---|---|
GI50 in FBS medium (nM) | 33.6±6.2 | 82.4±3.2 | >1000 | 24±2 | 22±3 | >1000 | >10 000 | >10 000 |
GI50 in DFBS medium (nM) | 27.1±6.4 | 46.5±3.1 | 257.3±38 | 16±1 | 14±1 | 102±27 | 205±96 | >10 000 |
