Table 2 Patient characteristics

From: Combination therapy: intermittent sorafenib with bevacizumab yields activity and decreased toxicity

 

DL 4, 5A, 5B ( n =17)

Ovarian cancer ( n =19 a , all DLs)

Characteristics

Value

 

Age, years

 Median

60

52.5

 Range

37–74 year old

40–61 year old

 No. of patients

17

19

ECOG performance status

 0

5

1

 1

12

18

Sex

 Female

14

19

 Male

3

0

Previous anticancer treatments

 All, median (range)

3 (1–7)

5 (1–11)

 Chemotherapy, median (range)

2 (1–7)

4 (1–9)b

 Radiation, median (range)

1 (1–5)

0

Tumour type

N=17

 

 Ovarian cancer

6

19a

 Uterine

3

 

 Cervical

2

 

 Breast

2

 

 Melanoma

1

 

 Sarcoma

1

 

 Basal cell cancer

1

 

 Urothelial cancer

1

 
  1. aPlatinum resistant (n=19), sensitive (n=0).
  2. bDose levels (DL) 4, 5 A/B: hormonal therapy (n=1), immunotherapy (n=1).
  3. Ovarian cancer: hormonal therapy (n=6), immunotherapy (n=2), targeted therapy (n=3).