Figure 5 | British Journal of Cancer

Figure 5

From: The low-molecular-weight heparin, nadroparin, inhibits tumour angiogenesis in a rodent dorsal skinfold chamber model

Figure 5

Microvessel maturity (pericyte coverage index) in control and nadroparin-treated animals. (A, B) Serial sections of FVIII- and αSMA-stained microvessels, respectively, in control hamsters. Weak αSMA staining is present around tumour microvessels, illustrating deficient pericyte coverage. Scale bar=25 μm. (C) Area fraction (percentage of stained pixels vs total number of pixels in binary images) of FVIII- and αSMA-stained cells. Columns=mean; Bars=s.d.; *P<0.001. (D) Microvessel pericyte coverage index. Columns=mean; Bars=s.d.; *P=0.012.

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