Table 2 Evolution of microvessel diameter, red blood cell velocity, and volumetric blood flow over time

From: The low-molecular-weight heparin, nadroparin, inhibits tumour angiogenesis in a rodent dorsal skinfold chamber model

 

Day 0

Day 3

Day 6

Day 9

Control (N=20)

 D (μm)

21.2±16.1

23.1±8.1

23.8±9.3

26.5±12.8*

 V (mm s–1)

0.3±0.1

0.4±0.1*

0.4±0.2*

0.3±0.1**

 VQ (pl s–1)

163.1±159

135.8±67*

151.6±108*

171.5±158*

Nadroparin (N=21)

 D (μm)

21.6±10.1

22.5±7.9

24.2±7.1*

24.4±8.0*

 V (mm s–1)

0.4±0.1***

0.5±0.2

0.4±0.1

0.4±0.1***

 VQ (pl s–1)

130.4±122***

161.7±118

151.9±102

156.8±120*

  1. Abbreviations: D=microvessel diameter; V=red blood cell velocity; VQ=volumetric blood flow; Data represent mean±s.d. *P<0.05 vs day 0. **P<0.05 vs days 3 and 6. ***P<0.05 vs untreated animals at corresponding time points.