Table 4 Survival statistics for 8-oxodG immunohistochemistry and conventional risk factors
From: 8-Hydroxydeoxyguanosine: a new potential independent prognostic factor in breast cancer
Patients ( n =173) | Mean survival (months) | P -value for BCSS | |
---|---|---|---|
Tumor size (T) | |||
1 | 110 | 68.7 | <0.01 |
2–4 | 63 | 63.5 | |
Nodal status (N) | |||
0 | 97 | 70.4 | <0.01 |
1–2 | 76 | 62.6 | |
Grade | |||
1–2 | 110 | 70.0 | <0.01 |
3 | 63 | 62.1 | |
Lymphatic vessel invasion | |||
Yes | 16 | 55.6 | NS |
No | 151 | 67.9 | |
Blood vessel invasion | |||
Yes | 9 | 58.2 | NS |
No | 158 | 67.6 | |
ER expression | |||
Positive | 140 | 69.0 | <0.01 |
Negative | 33 | 55.9 | |
PR expression | |||
Positive | 116 | 67.5 | <0.05 |
Negative | 57 | 64.3 | |
Ki-67 | |||
0–2 | 127 | 69.6 | <0.001 |
3 | 46 | 56.7 | |
Her-2 | |||
Positive | 22 | 60.8 | NS |
Negative | 151 | 67.6 | |
Histology | |||
Ductal | 140 | 66.4 | NS |
Other | 33 | 67.7 | |
8-oxodG immunohistochemistry | |||
Positive | 127 | 66.9 | <0.01 |
Negative | 23 | 49.5 | |
8-oxodG immunohistochemistry ductal histology | |||
Positive | 106 | 67.4 | <0.001 |
Negative | 17 | 42.1 |