Table 4 Survival statistics for 8-oxodG immunohistochemistry and conventional risk factors

From: 8-Hydroxydeoxyguanosine: a new potential independent prognostic factor in breast cancer

 

Patients ( n =173)

Mean survival (months)

P -value for BCSS

Tumor size (T)

 1

110

68.7

<0.01

 2–4

63

63.5

 

Nodal status (N)

 0

97

70.4

<0.01

 1–2

76

62.6

 

Grade

 1–2

110

70.0

<0.01

 3

63

62.1

 

Lymphatic vessel invasion

 Yes

16

55.6

NS

 No

151

67.9

 

Blood vessel invasion

 Yes

9

58.2

NS

 No

158

67.6

 

ER expression

 Positive

140

69.0

<0.01

 Negative

33

55.9

 

PR expression

 Positive

116

67.5

<0.05

 Negative

57

64.3

 

Ki-67

 0–2

127

69.6

<0.001

 3

46

56.7

 

Her-2

 Positive

22

60.8

NS

 Negative

151

67.6

 

Histology

 Ductal

140

66.4

NS

 Other

33

67.7

 

8-oxodG immunohistochemistry

 Positive

127

66.9

<0.01

 Negative

23

49.5

 

8-oxodG immunohistochemistry ductal histology

 Positive

106

67.4

<0.001

 Negative

17

42.1

 
  1. Abbreviations: BCSS=Breast cancer specific survival; ER=oestrogen receptor; NS=no statistical significance; PR=progesterone receptor; 8-oxodG=8-hydroxydeoxyguanosine.
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