Table 1 Summary of patient population, tumour sample information and sphere-forming capability

From: Expansion of CD133+ colon cancer cultures retaining stem cell properties to enable cancer stem cell target discovery

Case

Age/sex

Tumour stage

Tissue type

Expression of CD133 + /EpCAM + population (%)

Sphere formation

1

84/F

Stage I

Normal adjacent tissue

2.78

No

  

(T2, N0, MX, G3)

Adenocarcinoma

0.26

No

2

92/F

Stage I

Normal adjacent tissue

3.46

No

  

(T2, N0, MX, G2)

Adenocarcinoma

4.30

No

3

61/F

Stage I

Normal adjacent tissue

1.00

No

  

(T2, N0, MX, G2)

Adenocarcinoma

53.46

Yesa

4

88/F

Stage I

Normal adjacent tissue

3.90

No

  

(T2, N0, M0, G2)

Adenocarcinoma

23.00

Yesa

5

36/F

Stage I

Normal adjacent tissue

0.40

No

  

(T2, N0, MX, G2)

Mucinous adenocarcinoma

3.72

Yes

6

76/F

Stage IIA

Normal adjacent tissue

0.62

No

  

(T3, N0, MX, G2)

Adenocarcinoma

36.51

No

7

85/F

Stage IIA

Normal adjacent tissue

3.50

N/A

  

(T3, N0, M0, G2)

Mucinous adenocarcinoma

29.50

Yes

8

51/F

Stage IIA

Normal adjacent tissue

0.90

No

  

(T3, N0, MX, G3)

Adenocarcinoma

4.36

Yes

9

59/M

Stage IIA

Normal adjacent tissue

0.34

No

  

(T3, N0, MX, G2)

Adenocarcinoma

45.48

Yes

10

84/F

Stage IIIB

Normal adjacent tissue

5.22

No

  

(T3, N1, MX, G2)

Mucinous adenocarcinoma

36.52

Yesa

11

62/M

Stage IIIC

Normal adjacent tissue

1.09

Yes

  

(T4, N2, MX, G2)

Adenocarcinoma

36.41

Yesa

12

70/F

Stage IIIC

Normal adjacent tissue

1.53

Yes

  

(T3, N2, MX, G2)

Adenocarcinoma

84.65

Yes

13

38/F

Stage IV

Normal adjacent tissue

4.19

No

  

(T4, N2, M1, G2)

Adenocarcinoma (metastasis)

39.49

Yes

  1. Abbreviations: F=female; M=male; N/A=not available (due to contamination).
  2. aCell sorting performed. Sphere formation was observed only in the CD133+/EpCAM+ fraction, but not in the CD133−/EpCAM+ fraction.
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