Figure 1

(A) Reduction in lesion size. Reduction in lesion size by 100%, >50% but <100 and <50% at baseline (week 0), after imiquimod (week 10), after vaccination (week 20), primary end point (week 52) and follow-up (62 weeks after primary end point) in the group (n=19). (B) Lesion and symptom responses. Lesion response (complete disappearance of VIN on histology), symptom response (regression to mild/none symptoms), absence of HPV16 on biopsy at baseline (week 0), after imiquimod (week 10), after vaccination (week 20) and primary end point (week 52) in the group (n=19).