Table 1 Basic characteristics of the population. Univariate comparison

From: Predicting the risk of endometrial cancer in postmenopausal women presenting with vaginal bleeding: the Norwich DEFAB risk assessment tool

Factors

Cancer, n =149 (5%)

No cancer, n =2898 (95%)

P -value

Age (years)

64 (59–72)

59 (54–67)

<0.0001a

BMI (kg m−2)

31 (27–36)

28 (25–32)

<0.0001a

Diabetes

 Yes

25 (17%, 11–24%)

158 (5%, 5–6%)

<0.0001b

 No

124 (83%, 76–89%)

2740 (95%, 94–95%)

 

Hypertension

 Yes

56 (38%, 30–46%)

741 (26%, 24–27%)

0.001b

 No

93 (62%, 54–70%)

2157 (74%, 73–76%)

 

HRT duration (years)

9 (4–20)

5 (2–10)

0.243a

Breast cancer

 Yes

16 (11%, 6–17%)

178 (6%, 5–7%)

0.025b

 No

133 (89%, 83–94%)

2720 (94%, 93–95%)

 

Tamoxifen use (years)

4.5 (2–8)

3 (2–5)

0.091a

Amount of bleeding*

 Spotting

39 (27%, 20–35%)

611 (21%, 20–23%)

 

 Light

80 (55%, 46–63%)

1620 (57%, 55–59%)

0.289b

 Heavy

27 (18%, 13–26%)

614 (22%, 20–23%)

 

Frequency of bleeding*

 Single

36 (24%, 18–32%)

1541 (53%, 52–55%)

<0.0001b

 Recurrent

112 (76%, 68–82%)

1345 (47%, 45–48%)

 

Endometrial thickness (mm)

14.9 (11.0–21.0)

4.6 (3.0–7.8)

<0.0001a

  1. Abbreviations: BMI=body mass index; HRT=hormone replacement therapy.
  2. Values are median (inter-quartile range), number (percent, 95% CI of percent).
  3. aTwo-sample Wilcoxon rank sum test (Mann–Whitney test).
  4. bχ2-Test.
  5. *Percentages worked on less numbers from the overall due to missing values.