Table 4 Sensitivity, specificity, PPV, and NPV for DEFAB cut-offs of ⩾3 and ⩾5

From: Predicting the risk of endometrial cancer in postmenopausal women presenting with vaginal bleeding: the Norwich DEFAB risk assessment tool

 

DEFAB score ⩾3, estimate (95% CI)

DEFAB score ⩾5, estimate (95% CI)

Sensitivity

81.9% (74.7–87.7%)

67.8% (59.6–75.2%)

Specificity

50.1% (48.2–51.9%)

74.1 (72.5–75.7%)

ROC area

0.660 (0.627–0.692)

0.710 (0.671–0.748)

PPV

7.78% (6.50–9.21%)

11.9% (9.77–14.2%)

NPV

98.2% (97.4–98.8%)

97.8% (97.1–98.4%)

  1. Abbreviations: CI=confidence interval; NPV=negative predictive value; PPV=positive predictive value; ROC=receiver operating characteristic curve.
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