Table 3 Cox proportional hazard regression analysis for overall survival in 96 patients with ESCC

From: Prediction of CCND1 amplification using plasma DNA as a prognostic marker in oesophageal squamous cell carcinoma

 

Univariate a

Multivariate b

Factor

P- value

HR

95%CI

P- value

Sex

 Male vs female

0.8596

 

—

 

Age

 <65 vs 65≦

0.6148

 

—

 

Lymphatic invasion

 Negative vs positive

0.7233

 

—

 

Venous invasion

 Negative vs positive

0.1472

 

—

 

T stage

 T0/1/2 vs T3/4

0.0430

4.274

1.055–17.241

0.0419

N stage

 N0 vs N1

0.6650

 

—

 

Plasma CCND1/DRD2 ratio

 <1.33 vs 1.33≦

0.0186

5.988

1.232–29.411

0.0266

  1. Abbreviations: CCND1=cyclin D1; CI=confidence interval; DRD2=dopamine receptor D2; ESCC=oesophageal squamous cell carcinoma; HR=hazard ratio.
  2. aKaplan–Meier method, and the significance of difference was determined by log-rank test.
  3. bMultivariate survival analysis was performed using Cox’s proportional hazard model.
  4. Statistically significant values are in bold face type.
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