Table 1 Characteristics of study groups
From: Adipose tissue pathways involved in weight loss of cancer cachexia
Measure | Cancer – cachexia | Cancer – weight-stable | P -value |
|---|---|---|---|
Gender, M/F | 10/3 | 9/5 | 0.52 |
Age, years | 65±6 | 65±8 | 0.75 |
Body mass index (BMI), kg m−2 | 22.4±2.9 | 25.5±3.6 | 0.019 |
Body fat, % | 18.5±5.8 | 27.4±6.6 | 0.001 |
Body fat, kg | 12.7±4.7 | 21.0±5.0 | <0.001 |
Lean body mass, kg | 57.1±13.5 | 57.1±14.1 | 0.99 |
Weight loss, % of habitual weight | 9.7±4.0 | 0.6±3.1 | <0.001 |
P-glucose, mmol l−1 | 6.6±1.6 | 6.4±1.7 | 0.71 |
P-triglycerides, mmol l−1 | 1.1±0.4 | 1.4±0.5 | 0.059 |
P-cholesterol, mmol l−1 | 4.6±1.3 | 5.0±1.2 | 0.41 |
S-albumin, g l−1 | 34.6±3.9 | 38.2±2.7 | 0.012 |
S-CRP, mg l−1 | 23.5±36.1 | 2.2±1.8 | 0.002 |
S-interleukin-6, μg l−1 | 9.8±8.5 | 3.5±1.4 | 0.014 |
P-glycerol, μmol/l/kg body fat | 7.0±4.3 | 3.4±1.6 | 0.01 |
P-fatty acids, mmol/l/kg fat | 0.08±0.04 | 0.04±0.02 | 0.004 |
SGA score, points | 8 (3–17) | 2 (1–3) | <0.001 |
Tumour stage, points | 3 (1–4) | 4 (0–4) | 0.04 |
Respiratory quotient, VO2/VCO2 | 0.805±0.028 | 0.849±0.065 | 0.036 |
Resting energy expenditure, kcal day−1 | 1639±304 | 1654±293 | 0.89 |
Fat cell volume, pico litres | 331±137 | 504±146 | 0.006 |
Fat cell number × 1010 | 4.8±1.7 | 4.6±0.9 | 0.78 |
