Table 1 Relationship between HER2 amplification of primary cancer and that of CTC

From: Improving the yield of circulating tumour cells facilitates molecular characterisation and recognition of discordant HER2 amplification in breast cancer

Primary tumor

Total No. of patients

Patients with HER2−CTCs

Patients with HER2+CTCs a

Discordance

HER2+

45

1

44

2%

HER2−

30

20

10

33%

  1. Abbreviations: CTC=circulating cancer cells; HER2=human epidermal growth factor receptor 2.
  2. aHER2 positive defined as ratio of HER2/CEP17 ⩾2.0 by FISH.
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