Table 4 Correlations of BRAF mutations with MSI status and cyclin D1 expression in 144 patients

From: BRAF mutations, microsatellite instability status and cyclin D1 expression predict metastatic colorectal patients’ outcome

 

MSI status, N (%)

 

Cyclin D1, N (%)

  

High

Stable

 

Overexpressed

Weak expression

No expression

 
 

No of patients

22 (15)

122 (85)

P -value a

26 (18)

63 (44)

55 (38)

P -value a

BRAF V600E mutation

 Mutant

12

10 (83)

2 (17)

<0.001

7 (58)

3 (25)

2 (17)

0.001b

 Wild type

132

12 (9)

120 (91)

 

19 (14)

60 (46)

53 (40)

 
  1. Abbreviation: MSI=microsatellite instability.
  2. aFisher's exact test.
  3. bOverexpression vs weak or no expression.
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