Figure 2
From: Dichloroacetate induces apoptosis and cell-cycle arrest in colorectal cancer cells
Dichloroacetate induced a dose-dependent increase in percentage of the apoptotic population in the cancer cells with minimal apoptosis in the non-cancerous cells. Cells were treated with doses of DCA for 24 h (A) and 48 h (B), stained with annexin V-FITC and 7-AAD, and analysed with flow cytometry. Data points represent the mean (±s.d.) of three independent experiments for 0 and 50 mM DCA (* – significant difference relative to control).
