Figure 6
From: Dichloroacetate induces apoptosis and cell-cycle arrest in colorectal cancer cells

Dichloroacetate treatment reduced phosphorylation of PDHE1α at pSer293 site with no effect on the levels of total PDHE1α in all the cell lines investigated. Whole-cell lysates were prepared after treating cells with 20 mM DCA for 8 h and from untreated cells, and western blot analyses were performed.