Table 2b New grading system for size groups – recurrence of ipsilateral DCIS or invasive carcinoma

From: A new pathological system for grading DCIS with improved prediction of local recurrence: results from the UKCCCR/ANZ DCIS trial

Feature

Category

No. cases

No. events

HR (95% CI)

χ 2 for trend, P- value

Tumour size <9 mm

     

New grade, three tier

Low/intermediate

132

3

0.21 (0.05–0.71)

8.57

 

High

108

9

0.75 (0.32 – 1.71)

P=0.011

 

Very High

128

15

1.00a

 

Tumour size 10–19 mm

     

New grade, three tier

Low/intermediate

116

9

0.43 (0.21–0.90)

8.77

 

High

222

23

0.55 (0.33–0.91)

P=0.01

 

Very high

237

45

1.00a

 

Tumour size >20 mm

     

New grade, three tier

Low/intermediate

62

7

0.46 (0.31–1.15)

4.65

 

High

94

14

0.46 (0.20–1.06)

P=0.09

 

Very high

112

28

1.00a

 
  1. Abbreviations: CI=confidence interval; DCIS=ductal carcinoma in situ; HR=hazard ratio.
  2. aBaseline category.