Table 4 Multivariate analysis for all ipsilateral recurrent events and for recurrence of ipsilateral invasive disease

	Recurrence of all ipsilateral disease (DCIS or invasive)			Recurrence of ipsilateral invasive carcinoma
Covariate	No. cases	HR	95% CI	No. cases	HR	95% CI
New grading system
Low and intermediate	310	1^a		309	1^a
High	424	1.69	0.99–2.89	423	0.86	0.35–2.11
Very high	477	2.77	1.69–4.57	476	1.46	0.65–3.31
XRT received
No XRT	776	1^a		774	1^a
XRT	435	0.34	0.23–0.52	434	0.52	0.27–0.98
Tumour size
0–0.9 cm	368	1^a		366	1^a
1.0–1.9 cm	575	1.67	1.07–2.59	574	1.89	0.89–3.99
⩾2 cm	268	2.67	1.66–4.30	268	1.89	0.80–4.49
Excision
Complete	838	1^a		835	1^a
Incomplete	192	1.47	0.98–2.22	192	1.01	0.46–2.21
Uncertain	181	1.82	1.21–2.73	181	2.35	1.27–4.37
Inflammation
Absent				294	1^a
Present				914	3.11	1.06–9.13

Abbreviations: CI=confidence interval; DCIS=ductal carcinoma in situ; HR=hazard ratio; XRT=radiotherapy.
^aBaseline category.

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