Table 2 Osteosarcoma vs non-malignant bone

From: Osteosarcoma is characterised by reduced expression of markers of osteoclastogenesis and antigen presentation compared with normal bone

Probe ID

Symbol

Description and accession number

Fold change

P -value

A_23_P252306

ID1

Inhibitor of DNA binding 1, dominant-negative helix-loop-helix protein [NM_002165]

4.07

0.00276

A_23_P114232

PRDX4

Peroxiredoxin 4 [NM_006406]

3.63

0.00664

A_23_P216501

TPM2

Tropomyosin 2 (β) [NM_213674]

3.30

0.00237

A_23_P206724

MT1E

Metallothionein 1E [NM_175617]

3.11

0.00661

A_23_P334709

FKBP9

FK506-binding protein 9, 63 kDa [NM_007270]

3.08

0.0111

A_23_P163782

MT1H

Metallothionein 1H [NM_005951]

3.02

0.0169

A_24_P125096

MT1X

Metallothionein 1X [NM_005952]

2.72

0.0316

A_23_P372874

S100A13

S100 calcium-binding protein A13 [NM_005979]

2.66

0.00955

A_32_P94798

ANXA2

Annexin A2 [NM_001002857]

2.62

0.00359

A_23_P408095

DSTN

Destrin (actin depolymerising factor) [NM_001011546]

2.50

0.00140

A_23_P434809

S100A8

S100 calcium-binding protein A8 (calgranulin A) [NM_002964]

−100.00

0.00549

A_23_P37856

HBA1

Homo sapiens haemoglobin, α 1 (HBA1), mRNA [NM_000558]

−50.00

4.26E−10

A_23_P140384

CTSG

Cathepsin G [NM_001911]

−16.67

0.0222

A_23_P80867

VWA5B2

von Willebrand factor A domain containing 5B2 [AL834499]

−11.11

0.0222

A_23_P153741

AZU1

Azurocidin 1 (cationic antimicrobial protein 37) [NM_001700]

−6.67

0.0485

A_23_P22444

CFP

Properdin P factor, complement [NM_002621]

−6.25

0.0496

A_23_P208866

GMFG

Glia maturation factor, γ [NM_004877]

−5.88

0.00748

A_24_P207195

IRX3

Iroquois homeobox protein 3 [NM_024336]

−5.88

0.00263

A_23_P403886

GLYAT

Glycine-N-acyltransferase [NM_005838]

−5.56

0.00391

A_23_P156708

TNXB

Tenascin XB [NM_019105]

−5.56

0.00351

  1. Top 10 upregulated and 10 downregulated genes between osteosarcoma biopsies and non-malignant bone samples.