Table 3 Good response vs poor response

From: Osteosarcoma is characterised by reduced expression of markers of osteoclastogenesis and antigen presentation compared with normal bone

Genbank

Synonym

Common name

Fold change

P -value

NM_021103

TMSB10

Thymosin, β 10

5.34

0.0171

NM_000582

SPP1

Secreted phosphoprotein 1 (osteopontin, bone sialoprotein I, early T-lymphocyte activation 1)

4.82

0.0171

NM_006332

IFI30

Interferon, γ-inducible protein 30

4.36

0.0224

NM_002952

RPS2

Ribosomal protein S2

3.70

0.0487

NM_005514

HLA-B

Major histocompatibility complex, class I, B

3.56

0.0487

NM_000455

STK11

Serine/threonine kinase 11 (Peutz–Jeghers syndrome)

3.49

0.0249

NM_147780

CTSB

Cathepsin B

3.48

0.0355

NM_153461

IL17RC

Interleukin 17 receptor C

3.39

0.0415

NM_002032

FTH1

Ferritin, heavy polypeptide 1

3.32

0.0355

NM_005507

CFL1

Cofilin 1 (non-muscle)

3.29

0.0251

NM_002116

HLA-A

Major histocompatibility complex, class I, A

3.17

0.0379

NM_003332

TYROBP

TYRO protein tyrosine kinase-binding protein

3.16

0.0487

NM_001022

RPS19

Ribosomal protein S19

3.16

0.023

NM_053275

RPLP0

Ribosomal protein, large, P0

3.14

0.0439

NM_000992

RPL29

Ribosomal protein L29 a.k.a. heparin/eparan sulphate interacting protein (HIP)

3.11

0.0497

NM_002117

HLA-C

Major histocompatibility complex, class I, C

2.99

0.0401

NR_002205

FTHL12

Ferritin, heavy polypeptide-like 12

2.95

0.0392

NM_001404

EEF1G

Eukaryotic translation elongation factor 1 γ

2.93

0.0443

NM_001014

RPS10

Ribosomal protein S10

2.83

0.0171

NM_001003

RPLP1

Ribosomal protein, large, P1

2.81

0.0397

NM_003295

TPT1

Tumour protein, translationally controlled 1

2.66

0.0365

BC031631

CFLP1

Cofilin pseudogene 1

2.65

0.0232

NM_006435

IFITM2

Interferon induced transmembrane protein 2 (1-8D)

2.61

0.0489

NM_002948

RPL15

Ribosomal protein L15

2.60

0.0497

NM_001020

RPS16

Ribosomal protein S16

2.58

0.0355

NM_000982

RPL21

Ribosomal protein L21

2.56

0.0489

NM_178230

COAS2

Cyclophilin-LC

2.51

0.0444

NM_000979

RPL18

Ribosomal protein L18

2.50

0.0455

NM_001022

RPS19

Ribosomal protein S19

2.47

0.0392

NM_003295

TPT1

Tumour protein, translationally controlled 1

2.47

0.0439

BC034271

FANCC

Fanconi anaemia, complementation group C

2.45

0.0214

NM_001997

FAU

Finkel–Biskis–Reilly murine sarcoma virus (FBR-MuSV) ubiquitously expressed (fox derived); RPS30

2.45

0.043

NM_001006

RPS3A

Ribosomal protein S3A

2.45

0.0497

AY358369

SIGLEC5

Sialic acid-binding Ig-like lectin 5 (CD170)

2.45

0.0489

NM_181468

ITGB4BP

Integrin β 4-binding protein

2.40

0.0444

NM_000990

RPL27A

Ribosomal protein L27a

2.39

0.0392

NM_002489

NDUFA4

NADH dehydrogenase (ubiquinone) 1 α subcomplex, 4, 9 kDa

2.32

0.0439

AK098605

FMN2

Formin 2

2.32

0.0443

NM_001019

RPS15A

Ribosomal protein S15a

2.32

0.0401

NM_002107

H3F3A

H3 histone, family 3A

2.30

0.0303

NM_005620

S100A11

S100 calcium-binding protein A11 (calgizzarin)

2.30

0.0487

NM_006013

RPL10

Ribosomal protein L10

2.28

0.0489

NM_005009

NME4

Non-metastatic cells 4, protein expressed in

2.27

0.0365

NM_006886

ATP5E

ATP synthase, H+ transporting, mitochondrial F1 complex, å subunit

2.23

0.0171

NM_001008741

LOC388817

Peptidylprolyl isomerase A-like

2.23

0.0444

NM_032828

ZNF587

Zinc-finger protein 587

2.22

0.0487

NM_015933

HSPC016

Hypothetical protein HSPC016

2.22

0.0258

NM_024040

CUEDC2

CUE domain containing 2

2.19

0.0214

NM_006808

SEC61B

Sec61 β subunit

2.18

0.0465

NM_002406

MGAT1

Mannosyl (α-1,3-)-glycoprotein β-1,2-N-acetylglucosaminyltransferase

2.14

0.0415

NM_002797

PSMB5

Proteasome (prosome, macropain) subunit, β type, 5

2.13

0.0171

NM_001021

RPS17

Ribosomal protein S17

2.10

0.0489

NM_000182

HADHA

Hydroxyacyl-coenzyme A dehydrogenase/3-ketoacyl-coenzyme A thiolase/enoyl-coenzyme A hydratase (trifunctional protein), α subunit

2.07

0.0392

NM_012067

AKR7A3

Aldo-keto reductase family 7, member A3 (aflatoxin aldehyde reductase)

2.06

0.0224

XM_376787

RPS26P10

Ribosomal protein S26 pseudogene 10

2.06

0.043

NM_005340

HINT1

Histidine triad nucleotide-binding protein 1

2.04

0.0444

NM_145893

A2BP1

Ataxin 2-binding protein 1

−2.44

0.0357

NM_015503

SH2B1

SH2-B adaptor protein

−2.33

0.0487

NM_178033

CYP4X1

Cytochrome P450, family 4, subfamily X, polypeptide 1

−2.08

0.0487

NM_003893

LDB1

LIM domain-binding 1

−2.04

0.0355

CR749256

XRCC2

X-ray repair complementing defective repair in Chinese hamster cells 2

−2.00

0.0357

  1. Genes differentially expressed between biopsies of good responders and poor responders. The list shows 61 annotated genes from the original list of 123 genes.
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