Table 2 Mean and s.e.m. of age and biochemical indices for patient groups

From: Discovery of serum biomarkers for pancreatic adenocarcinoma using proteomic analysis

  

Pancreatic cancer

Disease controls

P -value

Values

Set

Mean

s.e.m. or range

Mean

s.e.m. or range

PC vs DC

Age (years)

Training

70.9

(28–80)

62.7

(32–81)

NS

 

Validation-2

69.7

(32–81)

57.1

(18–89)

NS

Urea (mmol l–1)

Training

5.9

0.5

5.1

0.4

NS

 

Validation-2

5.8

0.4

5.6

0.6

NS

Bilirubin (μmol l–1)

Training

144

33

18

3

0.001

 

Validation-2

88

20

49

21

0.01

Albumin (g l–1)

Training

35.1

1.2

41.1

0.8

0.001

 

Validation-2

35.5

1.1

39.4

1.1

0.017

AST (IU l–1)a

Training

111

19

50

10

0.001

 

Validation-2

98

19

53

9

0.049

ALT (IU l–1)a

Training

154

28

76

21

0.005

 

Validation-2

143

32

94

26

NS

ALP (IU l–1)a

Training

362

60

101

14

0.001

 

Validation-2

316

45

172

23

0.007

GGT (IU l–1)a

Training

489

102

130

43

0.001

 

Validation-2

561

111

208

49

0.006

CA19-9 (U l–1)a

Training

1594

960

32

7

0.001

 

Validation-2

1466

922

31

9

0.001

  1. Abbreviations: ALP= alkaline phosphatase; AST= glutamic-oxaloacetic transaminase; ALT= glutamic-pyruvic transaminase; CA19-9= carbohydrate antibody 19-9; DC= disease control; GGT= γ-glutamyltransferase; NS= not significant; PC= pancreatic cancer.
  2. aResults are for serum values.
  3. P-value indicates Mann–Whitney U-test result.
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