Figure 3

Kaplan–Meier survival curves illustrating probability of distant metastasis-free survival of breast cancer patients according to their HER2–PTK6 protein complex status. Patients with low PLA signals (⩽0.5, solid line) are associated with better prognosis (21% of patients developed distant metastases), whereas from patients with higher PLA signal counts (>0.5, dashed line) 50% suffer from distant metastases. (Mean PLA was defined as mean number of PLA signals per 1000 pixels of tumour area in the section).