Table 1 Age and age-adjusted baseline characteristics of men, ATBC Study

From: Insulin-like growth factors and liver cancer risk in male smokers

Characteristic

Cases ( n =50)

Comparison group ( n =400)

P- value

Age at randomisation (years)

60 (0.7)

56 (0.2)

<0.01

Height (cm)

174.0 (0.9)

173.7 (0.3)

0.79

Weight (kg)

82.1 (1.9)

80.3 (0.7)

0.38

BMI (kg m−2)

27.0 (0.6)

26.6 (0.2)

0.45

Serum total cholesterol (mmol l−1)

6.0 (0.2)

6.3 (0.1)

0.04

Alcohol intake (g per day)

22.3 (3.6)

19.2 (1.2)

0.43

Smoking history

 No. of cigarettes per day

23.7 (1.2)

20.3 (0.4)

<0.01

 No. of years smoked

36.8 (1.0)

35.3 (0.3)

0.16

Physical activity – leisure, n (%)

0.01

 Light

31 (65.4)

172 (42.6)

<0.01

 Moderate

18 (33.4)

204 (51.3)

0.02

 Heavy

1 (1.2)

24 (6.1)

0.16

Medical history

 Diabetes, n (%)

5 (9.4)

18 (4.6)

0.16

 Gallstones, n (%)

2 (2.9)

21 (5.4)

0.47

Insulin-like growth factor-I (ng ml−1)

115.2 (7.3)

146.3 (2.5)

<0.01

Insulin-like growth factor BP-3 (ng ml−1)

2017.8 (92.5)

2387.9 (31.9)

<0.01

IGF-I/IGFBP-3 molar ratio

0.21 (0.01)

0.22 (0.003)

0.07

  1. Abbreviations: ATBC=α-Tocopherol, β-Carotene Cancer Prevention; BMI=body mass index; IGF-I=insulin-like growth factor-I; IGFBP-3=IGF binding protein-3
  2. Means (s.e.) are reported unless otherwise indicated.
  3. P-values from generalised linear models.