Table 1 Age and age-adjusted baseline characteristics of men, ATBC Study
From: Insulin-like growth factors and liver cancer risk in male smokers
Characteristic | Cases ( n =50) | Comparison group ( n =400) | P- value |
|---|---|---|---|
Age at randomisation (years) | 60 (0.7) | 56 (0.2) | <0.01 |
Height (cm) | 174.0 (0.9) | 173.7 (0.3) | 0.79 |
Weight (kg) | 82.1 (1.9) | 80.3 (0.7) | 0.38 |
BMI (kg m−2) | 27.0 (0.6) | 26.6 (0.2) | 0.45 |
Serum total cholesterol (mmol l−1) | 6.0 (0.2) | 6.3 (0.1) | 0.04 |
Alcohol intake (g per day) | 22.3 (3.6) | 19.2 (1.2) | 0.43 |
Smoking history | |||
No. of cigarettes per day | 23.7 (1.2) | 20.3 (0.4) | <0.01 |
No. of years smoked | 36.8 (1.0) | 35.3 (0.3) | 0.16 |
Physical activity – leisure, n (%) | 0.01 | ||
Light | 31 (65.4) | 172 (42.6) | <0.01 |
Moderate | 18 (33.4) | 204 (51.3) | 0.02 |
Heavy | 1 (1.2) | 24 (6.1) | 0.16 |
Medical history | |||
Diabetes, n (%) | 5 (9.4) | 18 (4.6) | 0.16 |
Gallstones, n (%) | 2 (2.9) | 21 (5.4) | 0.47 |
Insulin-like growth factor-I (ng ml−1) | 115.2 (7.3) | 146.3 (2.5) | <0.01 |
Insulin-like growth factor BP-3 (ng ml−1) | 2017.8 (92.5) | 2387.9 (31.9) | <0.01 |
IGF-I/IGFBP-3 molar ratio | 0.21 (0.01) | 0.22 (0.003) | 0.07 |