Figure 6 | British Journal of Cancer

Figure 6

From: Selective cyclooxygenase-2 silencing mediated by engineered E. coli and RNA interference induces anti-tumour effects in human colon cancer cells

Figure 6

Effect of COX-2 silencing mediated by InvColi-pS on CRC cell invasiveness. Invasion index was evaluated in (A) HT-29 and (B) HCA-7 cells, 48 h after InvColi strain infection. The invasion assay was performed using Boyden chambers and 8-μm polycarbonate membranes coated with Matrigel (40-fold dilution). Samples were tested in the absence (dark bars) and in the presence (light bars) of PMA 40 nM. Relative invasion index refers to HT-29 and HCA-7 cells infected with InvColi-pS−, not treated with PMA. Data represent mean±s.e.m. of three independent experiments. *P<0.01.

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