Table 2 The relationship between clinicopathological characteristics and cancer-specific survival in patients undergoing surgery for Dukes B rectal cancer: univariate and multivariate analysis
Univariate analysis | Multivariate analysis | ||||
---|---|---|---|---|---|
Risk factor | Patients ( n =430) | Hazard ratio (95% CI) | P -value | Hazard ratio (95% CI) | P -value |
Age (<75/⩾75 years) | 302/128 | 1.65 (1.19–2.27) | 0.002 | 1.58 (1.14–2.18) | 0.006 |
Sex (female/male) | 186/244 | 1.18 (0.87–1.60) | 0.298 | ||
Deprivationa (intermediate) | 65/260/105 | 0.95 (0.63–1.45) | 0.812 | ||
(deprived) | 0.93 (0.58–1.50) | 0.767 | |||
Mode of presentation (elective/emergency) | 364/66 | 1.56 (1.06–2.28) | 0.023 | 1.44 (0.98–2.12) | 0.062 |
Specialisation (yes/no) | 122/299 | 1.09 (0.77–1.53) | 0.625 | ||
Anastomotic leak (no/yes) | 409/21 | 1.25 (0.66–2.37) | 0.495 | ||
Adjuvant therapy (no/yes) | 348/22 | 1.62 (0.88–3.01) | 0.124 |