Table 1 Clinical and pathological characteristics

From: Adjuvant chemoradiotherapy of advanced resectable rectal cancer: results of a randomised trial comparing modulation of 5-fluorouracil with folinic acid or with interferon-α

 

Treatment

 

Patients Number

5-FU ( N =282)

5-FU+FA ( N =291)

5-FU+IFN α (N =223)

Total ( N =796)

Age (years)

 Median

61.6

61.4

61.2

61.4

 Range

31.5–81.4

23.0–81.4

29.6–86.3

23.0–86.3

Sex

 Male

180

191

140

511

 Female

102

100

83

285

Type of resection a

 ARb

135

126

98

359

 APR

60

78

50

188

 Unknown

87

87

75

249

UICC stage

 II

93

97

81

271

A T3 N0

85

89

71

245

B T4 N0

8

8

10

26

 III

189

194

142

525

A T1/2 N1

26

25

20

71

B T3/4 N1

76

87

64

227

C T1–4 N2

87

82

58

227

Tumour depth (T)

 1

3

2

4

9

 2

33

35

18

86

 3

225

227

182

634

 4

21

27

19

67

Lymph nodes (N)

 0

93

97

81

271

 1

102

112

84

298

 2

87

82

58

227

Grading (G)

 1+2

212

219

174

605

 3

55

61

42

158

 Unknown

15

11

7

33

  1. Abbreviations: AR=anterior resections; APR=abdominoperineal resections; FA=folinic acid; 5-FU=5-fluorouracil; IFNα=interferon-α; UICC=International Union Against Cancer.
  2. aType of resection was determined retrospectively.
  3. bIncluding Hartmann procedures (5-FU, n=3; 5-FU+FA, n=3; 5-FU+INFα, n=3; total, n=9).
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