Table 1 Frequency distribution of demographic factors, comorbidities, and prescription medication use among colorectal cancer cases and matched controls in Northern Denmark, 1991–2008. (number, %)

	Cases		Controls
	N=9979	%	N=99 790	%
Gender
Women	4927	49	49 270	49
Men	5052	51	50 520	51
Diabetes
No	9210	92	93 291	94
Yes	769	7.7	6499	6.5
Alcoholism ^a
No	9719	97	97 587	98
Yes	260	2.6	2203	2.2
Inflammatory bowel disease
No	9917	99	99 253	100
Yes	62	0.6	537	0.5
NSAIDs
Never/rare use	6156	62	60 146	60
Recent use (1–3 years)	2330	23	25 187	25
Former use (3+ years)	1493	15	14 457	15
Aspirin ^b
Never/rare use	7846	79	77 987	78
Recent use (1–3 years)	1892	19	19 374	19
Former use (3+ years)	241	2.4	2429	2.4
Statins
Never/rare use	9268	93	92 061	92
Recent use (1–3 years)	688	6.9	7499	7.5
Former use (3+ years)	23	0.2	230	0.2
Post-menopausal hormone replacement therapy
Never/rare use	8913	89	88 190	88
Recent use (1–3 years)	708	7.1	7673	7.7
Former use (3+ years)	358	3.6	3927	3.9
Neuroleptics
Never/rare use	9424	94	93 686	94
Recent use (1–3 years)	343	3.4	4043	4.1
Former use (3+ years)	212	2.1	2061	2.1
Marital status
Married	5649	57	56 602	57
Never married	698	7.0	7202	7.2
Divorced or widowed	3632	36	35 986	36

Abbreviation: NSAIDs=non-steroidal anti-inflammatory drugs.
^aThe definition of alcoholism included prescriptions of disulfiram as a proxy for chronic alcohol abuse.
^bLow- and high-dose aspirin were grouped together.

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