Figure 3

Kaplan–Meier plots of PFS in Study 1002 patients. (A) All patients with available baseline fIGF-1 level data (N=110). (B and C) Patients with baseline fIGF-1 ⩽0.7 (B, N=64) or >0.7 ng ml−1 (C, N=46). (D) All patients with available baseline insulin/IGFBP-1 ratio data (N=82). (E and F) Patients with baseline insulin/IGFBP-1 ratio ⩽0.7 (E, N=34) or >0.7 ng ml−1 (F, N=48).