Figure 6
From: LY6K is a novel molecular target in bladder cancer on basis of integrate genome-wide profiling
Effects of LY6K knockdown in T24/LY6K transfectant on cell growth, migration, and invasion. (A) LY6K mRNA expressions were markedly lower after si-LY6K-transfection of T24/LY6K transfectant (TF) than in the si-control transfectant. (B) Cell viability as determined by XTT assay. Significant growth inhibition was observed in the si-LY6K transfectant. (C) Cell migration activity by the wound healing assay. A significant inhibition of cell migration was observed in the si-LY6K transfectant. (D) Cell invasion activity by the matrigel invasion assay. The number of cells invading through the membrane was significantly decreased in the si-LY6K transfectant.
