Table 3 Frequently upregulated genes on chromosome 8q24.3 in bladder cancer cell lines

From: LY6K is a novel molecular target in bladder cancer on basis of integrate genome-wide profiling

   

Fold change (relative to normal bladder)

Gene ID

Symbol

Gene name

BOY

J82

KK47

T24

UMUC

Average

54742

LY6K

Lymphocyte antigen 6 complex, locus K

40.92

34.89

41.53

20.08

5.70

28.62

8629

JRK

Jerky homolog (mouse)

27.01

7.69

32.34

4.28

6.09

15.48

9401

RECQL4

RecQ protein-like 4

19.39

12.65

16.89

9.96

10.47

13.87

286077

FAM83H

Family with sequence similarity 83, member H

9.91

5.43

48.10

4.50

0.22

13.63

23246

BOP1

Block of proliferation 1

19.73

6.17

16.23

6.16

11.67

11.99

65263

PYCRL

Pyrroline-5-carboxylate reductase-like

18.65

8.13

15.94

5.00

9.25

11.39

80728

KIAA1688

KIAA1688 protein

14.73

8.10

18.85

6.34

6.88

10.98

4796

NFKBIL2

Nuclear factor of Îş light polypeptide gene enhancer in B-cells inhibitor-like 2

16.07

5.28

13.46

6.83

10.47

10.42

286075

ZNF707

Zinc-finger protein 707

15.16

5.27

15.58

3.47

5.93

9.08

9684

LRRC14

Leucine-rich repeat containing 14

10.97

9.17

17.30

5.04

2.33

8.96

54512

EXOSC4

Exosome component 4

13.90

4.13

13.84

4.12

6.12

8.42

113655

MFSD3

Major facilitator superfamily domain containing 3

9.41

6.63

11.33

3.33

6.46

7.43

51236

C8orf30A

Chromosome 8 open reading frame 30A

10.67

4.59

9.19

3.88

5.83

6.83

4061

LY6E

Lymphocyte antigen 6 complex, locus E

6.02

7.31

10.70

2.07

5.74

6.37

9831

ZNF623

Zinc-finger protein 623

8.57

4.81

8.27

1.79

5.91

5.87

7264

TSTA3

Tissue-specific transplantation antigen P35B

7.25

2.93

10.85

3.47

3.72

5.64

1537

CYC1

Cytochrome c-1

7.88

3.96

9.05

1.96

4.55

5.48

23144

ZC3H3

Zinc-finger CCCH-type containing 3

7.22

2.74

9.19

2.41

4.84

5.28

28991

COMMD5

COMM domain containing 5

9.54

4.50

6.22

2.49

3.28

5.20

84875

PARP10

Poly (ADP-ribose) polymerase family, member 10

6.00

6.36

7.75

3.23

2.34

5.14

22827

PUF60

Poly-U-binding splicing factor 60 KDa

9.97

2.56

7.85

1.95

3.04

5.08

54108

CHRAC1

Chromatin accessibility complex 1

7.53

2.90

8.54

2.11

4.13

5.04

27161

EIF2C2

Eukaryotic translation initiation factor 2C, 2

9.83

1.98

6.74

1.97

3.14

4.73

84948

TIGD5

Tigger transposable element derived 5

6.12

4.47

6.86

1.61

4.33

4.68

84988

PPP1R16A

Protein phosphatase 1, regulatory (inhibitor) subunit 16A

5.06

2.54

10.52

1.83

3.36

4.66

26233

FBXL6

F-box and leucine-rich repeat protein 6

6.95

2.57

7.40

2.64

3.45

4.60

2738

GLI4

GLI-Kruppel family member GLI4

8.28

2.60

5.15

1.90

4.65

4.52

55630

SLC39A4

Solute carrier family 39 (zinc transporter), member 4

10.17

3.38

2.08

3.07

0.84

3.91

6132

RPL8

Ribosomal protein L8

7.12

1.86

7.13

1.33

2.05

3.90

575

BAI1

Brain-specific angiogenesis inhibitor 1

2.50

1.52

2.20

2.53

9.78

3.71

23513

SCRIB

Scribbled homologue (Drosophila)

7.46

1.81

5.32

1.56

2.35

3.70

2765

GML

Glycosylphosphatidylinositol anchored molecule like protein

5.18

4.34

4.46

2.68

1.68

3.67

5747

PTK2

Protein tyrosine kinase 2

7.73

2.24

2.84

1.76

3.77

3.67

79581

GPR172A

G protein-coupled receptor 172A

5.08

2.83

5.33

2.04

2.93

3.64

2875

GPT

Glutamic-pyruvate transaminase (alanine aminotransferase)

3.20

3.36

2.28

3.01

6.15

3.60

7553

ZNF7

Zinc-finger protein 7

5.71

2.46

5.24

1.67

2.69

3.55

286122

C8orf31

Chromosome 8 open reading frame 31

4.01

1.86

7.06

1.62

2.38

3.39

286128

ZFP41

Zinc-finger protein 41 homolog (mouse)

6.34

3.50

3.41

2.11

1.50

3.37

81858

SHARPIN

SHANK-associated RH domain interactor

5.16

2.77

4.26

1.64

2.61

3.29

114822

RHPN1

Rhophilin, Rho GTPase-binding protein 1

5.25

1.09

5.86

2.45

1.64

3.26

1E+08

UNQ601

LPPA601

3.28

1.92

5.75

1.51

3.23

3.14

79943

ZNF696

Zinc-finger protein 696

5.60

1.52

3.45

2.17

2.91

3.13

8928

FOXH1

Forkhead box H1

4.56

2.32

3.38

2.13

3.24

3.13

8733

GPAA1

Glycosylphosphatidylinositol anchor attachment protein 1 homolog (yeast)

4.50

2.32

4.44

1.22

2.55

3.01

340390

KIAA1875

KIAA1875

3.59

1.93

5.25

1.80

2.23

2.96

340371

NRBP2

Nuclear receptor-binding protein 2

4.13

2.32

4.67

1.18

2.31

2.92

116447

TOP1MT

Topoisomerase (DNA) I, mitochondrial

5.50

1.15

4.17

0.97

2.56

2.87

90990

KIFC2

Kinesin family member C2

1.15

4.41

2.32

2.14

4.04

2.81

2907

GRINA

Glutamate receptor, ionotropic, N-methyl D-aspartate-associated protein 1 (glutamate binding)

4.50

2.51

3.57

0.73

1.52

2.57

1936

EEF1D

Eukaryotic translation elongation factor 1 delta (guanine nucleotide exchange protein)

3.20

1.60

4.90

1.16

1.39

2.45

8694

DGAT1

Diacylglycerol O-acyltransferase homolog 1 (mouse)

3.78

1.16

3.97

0.71

2.37

2.40

7564

ZNF16

Zinc-finger protein 16

4.34

1.23

3.58

0.86

1.97

2.40

1584

CYP11B1

Cytochrome P450, family 11, subfamily B, polypeptide 1

3.01

1.91

3.00

1.48

1.92

2.27

100130274

LOC100130274

Similar to hCG1646697

3.40

1.57

2.62

1.52

1.66

2.15

58500

ZNF250

Zinc-finger protein 250

3.47

1.74

2.22

1.02

1.91

2.07

203054

ADCK5

aarF domain containing kinase 5

2.47

2.05

3.23

1.06

1.26

2.01

Other LY6 family genes

137797

LYPD2

LY6/PLAUR domain containing 2

1.75

1.56

1.90

0.91

0.57

1.34

66004

LYNX1

Ly6/neurotoxin 1

1.15

0.60

1.05

0.55

1.10

0.89

57152

SLURP1

Secreted LY6/PLAUR domain containing 1

0.80

0.51

0.72

0.16

0.44

0.53

4062

LY6H

Lymphocyte antigen 6 complex, locus H

0.44

0.38

0.41

0.35

0.25

0.37

8581

LY6D

Lymphocyte antigen 6 complex, locus D

0.15

0.09

0.18

0.07

0.10

0.12

Back to article page