Figure 2 | British Journal of Cancer

Figure 2

From: Antiproliferative and proapoptotic activity of GUT-70 mediated through potent inhibition of Hsp90 in mantle cell lymphoma

Figure 2Figure 2

GUT-70-induced cell growth inhibition, apoptosis, and cell cycle arrest in MCL. (A) JVM-2, Granta 519, Jeko-1, and MINO cells were treated with the indicated concentrations of GUT-70 for 48 h, and the percentages of apoptotic cells were quantified by annexin V/PI staining. (B) Representative flow cytometric histograms of PI-treated cells after 24 h of GUT-70 treatment at indicated concentrations. The percentages of G0/G1-, S- and G2/M-phase cells were assessed in total viable cells (bar graphs).

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