Figure 1

Structure of FKBP5 with its major domains that are critical for its function as well as with the list of its interactive proteins by domain. AKT=a serine/threonine protein kinase, also called PKB; AR=androgen receptor; FK=FKBP-type domain; GR=glucocorticoid receptor; Hsp90=heat shock protein 90; IKKα=IκB kinase α subunit; PHLPP=PH domain and leucine-rich repeat protein phosphatases; PR=progesterone receptor; TPR=tetratricopeptide repeat.