Figure 4

Effects of IκBαM overexpression on gastric cancer xenografts. (A–C) The frequencies of immunopositive cells for PCNA (A) or HIF-1α (B) and the areas of blood vessels immunostained for CD31 (C) in differently sized gastric cancer xenografts (n=7) were quantified. Values represent means±s.d. and were determined using the Student's t-test. *P<0.05 vs SNU-668Vector. (D) Immunoblotting analysis of HIF-1α expression in similarly sized xenograft tumours.