Table 2 Spearman's correlation coefficients of pancreatic juice vs pancreatic tissue in ductal adenocarcinoma samples only

Gene	Sig. (two-tailed) P- value	Q -value (FDR)	Gene	Sig. (two-tailed) P- value	Q -value (FDR)
CPB1	0.108	0.358	IL8	0.265	0.421
TFF2	0.770	0.446	MSLN	0.667	0.444
EGFR	0.019^*	0.145	NMU	0.104	0.358
IGFBP3	0.667	0.444	NNMT	0.610	0.444
AMACR	0.200	0.421	POSTN	0.787	0.446
ARMET	0.787	0.446	SLPI	0.405	0.421
JAG1	0.397	0.421	CDH3	0.505	0.429
KRT7	0.787	0.446	GPRC5A	0.433	0.421
MMP11	0.289	0.421	LCN2	0.332	0.421
MTA1	0.624	0.444	NQO1	0.955	0.521
NME1	0.294	0.421	PLAT	0.420	0.421
S100P	0.987	0.521	PRSS2	0.117	0.358
SPINK1	0.326	0.421	PSCA	0.468	0.421
ANXA1	0.002^*	0.03	TIMP1	0.603	0.444
CEACAM6	0.460	0.421	KLK3	Not expressed	Not expressed

Abbreviations: ARMET=now called MANF, mesencephalic astrocyte-derived neurotrophic; AMACR=α-methylacyl-CoA racemase; ANXA1=annexin A1; CPB1=carboxypeptidase B1; CDH3=cadherin 3, type 1, P-cadherin (placental); CEACAM6=carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen); EGFR=epidermal growth factor receptor; FDR=false discovery rate; GPRC5A=G protein-coupled receptor family C, group5 member A factor; IL8=interleukin 8; IGFBP3=insulin-like growth factor binding protein 3; JAG1=jagged 1; KLK3=kallikrein-related peptidase 3; KRT7=keratin 7; LCN2=lipocalin 2; MSLN=mesothelin; MMP11=matrix metallopeptidase 11 (stromelysin 3); MTA1=metastasis associated 1; NQO1=NAD(P)H dehydrogenase, quinone 1; NMU=neuromedin U; NNMT=nicotinamide N-methyltransferase; NME1=non-metastatic cells 1, protein (NM23A) expressed in; PLAT=plasminogen activator, tissue; PRSS2=protease, serine, 2 (trypsin 2); PSCA=prostate stem cell antigen; POSTN=periostin, osteoblast specific factor; S100P=S100 calcium binding protein P; SPINK1=serine peptidase inhibitor, Kazal type 1; SLPI=secretory leukocyte peptidase inhibitor; TFF2=trefoil factor 2; TIMP=TIMP metallopeptidase inhibitor 1. ^*P<0.05.

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