Figure 4
From: Attenuated reovirus displays oncolysis with reduced host toxicity
AV reovirus retains its oncolytic activity in vitro. (A) HT1080, L929 and HCT116 cells were either mock infected or infected with WT or AV reovirus at an MOI of 40. At 48 h post-infection, viral cytopathic effects were photographed. (B) HT1080, L929 and HCT116 cells grown to 70% confluency were infected with WT or AV reovirus at a MOI of 20. Cell lysates were collected at the indicated timepoints and using equal loading, were analysed by immunoblotting with polyclonal reovirus antiserum.
