Figure 1

(A) Distribution of likelihood ratio P-values in KRAS wt patients by gene rank (disease control). Note: and += genes significantly associated with outcome, unadjusted P-value <0.05, = genes associated with outcome controlling for FDR <0.05, ^*= genes not significantly associated with outcome. In total, 110 genes depicted. (B) Distribution of likelihood ratio P-values in KRAS wt patients by gene rank (objective response). Note: and += genes significantly associated with outcome, unadjusted P-value <0.05, = genes associated with outcome controlling for FDR <0.05, ^*= genes not significantly associated with outcome. In total, 110 genes depicted. (C) Distribution of likelihood ratio P-values in KRAS wt patients by gene rank (PFS). Note: and += genes significantly associated with outcome, unadjusted P-value <0.05, = genes associated with outcome controlling for FDR <0.05, ^*= genes not significantly associated with outcome. In total, 110 genes depicted.