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Serial analysis of gene expression identifies putative metastasis-associated transcripts in colon tumour cell lines
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  • Published: 22 August 2000

Serial analysis of gene expression identifies putative metastasis-associated transcripts in colon tumour cell lines

  • A Parle-McDermott1,
  • P McWilliam1,
  • O Tighe1,
  • D Dunican1 &
  • …
  • D T Croke1 

British Journal of Cancer volume 83, pages 725–728 (2000)Cite this article

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Abstract

We have used serial analysis of gene expression (SAGE) to identify gene expression differences between a primary colon tumour cell line (SW480) and an isogenic lymph-node metastasis cell line (SW620). Differential expression was confirmed for the following genes: keratin K5, cystatin S, serum amyloid A, the human homologue of yeast ribosomal S28 and the p32 subunit of human pre-mRNA splicing factor SF2. Expression of confirmed differences were also analysed in other metastatic cell lines. © 2000 Cancer Research Campaign

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  • 16 November 2011

    This paper was modified 12 months after initial publication to switch to Creative Commons licence terms, as noted at publication

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Authors and Affiliations

  1. Department of Biochemistry, Royal College of Surgeons in Ireland, 123 St Stephen’s Green, Dublin, 2, Ireland

    A Parle-McDermott, P McWilliam, O Tighe, D Dunican & D T Croke

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  1. A Parle-McDermott
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  2. P McWilliam
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  3. O Tighe
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From twelve months after its original publication, this work is licensed under the Creative Commons Attribution-NonCommercial-Share Alike 3.0 Unported License. To view a copy of this license, visit http://creativecommons.org/licenses/by-nc-sa/3.0/

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Parle-McDermott, A., McWilliam, P., Tighe, O. et al. Serial analysis of gene expression identifies putative metastasis-associated transcripts in colon tumour cell lines. Br J Cancer 83, 725–728 (2000). https://doi.org/10.1054/bjoc.2000.1330

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  • Received: 20 October 1999

  • Revised: 11 April 2000

  • Accepted: 11 May 2000

  • Published: 22 August 2000

  • Issue date: 01 September 2000

  • DOI: https://doi.org/10.1054/bjoc.2000.1330

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Keywords

  • SAGE
  • colon
  • differential
  • metastasis
  • expression

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