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Does surgery modify growth kinetics of breast cancer micrometastases?
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  • Hypothesis
  • Open access
  • Published: 14 August 2001

Does surgery modify growth kinetics of breast cancer micrometastases?

  • R Demicheli1,
  • P Valagussa1 &
  • G Bonadonna1 

British Journal of Cancer volume 85, pages 490–492 (2001)Cite this article

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Abstract

Surgery should be considered as a major perturbing factor for metastasis development in laboratory animals. The different time distribution of mortality for 1173 patients undergoing mastectomy in comparison with 250 untreated patients suggests that primary tumour removal could result in changes of the metastatic process even for breast cancer. © 2001 Cancer Research Campaign http://www.bjcancer.com

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Change history

  • 16 November 2011

    This paper was modified 12 months after initial publication to switch to Creative Commons licence terms, as noted at publication

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Author information

Authors and Affiliations

  1. Istituto Nazionale Tumori via Venezian 1, Milano, 20133, Italy

    R Demicheli, P Valagussa & G Bonadonna

Authors
  1. R Demicheli
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  2. P Valagussa
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  3. G Bonadonna
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From twelve months after its original publication, this work is licensed under the Creative Commons Attribution-NonCommercial-Share Alike 3.0 Unported License. To view a copy of this license, visit http://creativecommons.org/licenses/by-nc-sa/3.0/

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Demicheli, R., Valagussa, P. & Bonadonna, G. Does surgery modify growth kinetics of breast cancer micrometastases?. Br J Cancer 85, 490–492 (2001). https://doi.org/10.1054/bjoc.2001.1969

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  • Received: 26 March 2001

  • Revised: 14 May 2001

  • Accepted: 21 May 2001

  • Published: 14 August 2001

  • Issue date: 17 August 2001

  • DOI: https://doi.org/10.1054/bjoc.2001.1969

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Keywords

  • breast cancer
  • growth kinetics
  • micrometastases
  • surgery signals
  • tumour dormancy

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