Table 1 Effect of sample sizes on the results of epistatic QTL analysis (100 replicates)
From: A penalized maximum likelihood method for estimating epistatic effects of QTL
QTL | Main effect | Interaction | σ2 | ||||||
|---|---|---|---|---|---|---|---|---|---|
Power | Position | Effect | Power | Position 1 | Position 2 | Effect | |||
1 | True value | — | 0.00 | 1.0000 | — | 0.00 | 80.00 | 1.0000 | 10.0000 |
n=200 | 63 | 3.02(5.86) | 1.0507(0.2852) | 51 | 4.86(9.61) | 82.38(25.81) | 0.9975(0.2506) | 10.7410(1.4764) | |
n=500 | 92 | 1.22(4.41) | 0.9104(0.1859) | 93 | 0.72(3.05) | 78.44(8.77) | 0.9427(0.1879) | 9.9434(0.7291) | |
2 | True value | — | 60.00 | 1.4142 | — | 40.00 | 140.00 | 1.4142 | |
n=200 | 85 | 58.71(5.30) | 1.4993(0.2908) | 87 | 42.17(13.50) | 137.74(14.33) | 1.4178(0.3755) | ||
n=500 | 100 | 60.23(1.79) | 1.4247(0.1804) | 100 | 39.24(4.78) | 139.50(5.14) | 1.3787(0.1856) | ||
3 | True value | — | 140.00 | 2.0000 | — | 80.00 | 200.00 | 2.0000 | |
n=200 | 100 | 139.75(2.65) | 1.9811(0.2906) | 98 | 79.53(3.65) | 199.37(2.71) | 1.9659(0.3050) | ||
n=500 | 100 | 140.01(0.09) | 1.9865(0.1634) | 100 | 79.98(0.27) | 200.00(0.00) | 2.0079(0.1684) | ||
4 | True value | — | 180.00 | 2.8284 | — | 100.00 | 120.00 | 2.8284 | |
n=200 | 100 | 179.89(1.86) | 2.8074(0.3012) | 98 | 99.30(3.61) | 120.10(1.67) | 2.6130(0.4750) | ||
n=500 | 100 | 179.99(0.08) | 2.8205(0.1856) | 100 | 99.98(0.16) | 120.00(0.00) | 2.8166(0.2048) | ||
