Table 3 Sample sizes required to gain 80% power of the POET according to the asymptotical power calculation formula and the actual powers associated with these sample sizes, having the marker allele frequency 0.2
From: A simple method for detection of imprinting effects based on case–parents trios
γ2 | I | γ1 | P | |||
|---|---|---|---|---|---|---|
0.01 | 0.1 | 0.5 | 0.8 | |||
2 | 0.0125 | 1.25 | 422680 (0.804) | 4741 (0.804) | 5228 (0.802) | 50223 (0.796) |
0.0250 | 1.50 | 106954 (0.800) | 1312 (0.795) | 1557 (0.801) | 13697 (0.797) | |
0.0125 | 1.75 | 433004 (0.802) | 5805 (0.799) | 7340 (0.799) | 59571 (0.798) | |
4 | 0.0375 | 1.75 | 48125 (0.805) | 662 (0.803) | 1430 (0.802) | 19029 (0.801) |
0.0750 | 2.50 | 12465 (0.800) | 213 (0.800) | 493 (0.801) | 5468 (0.808) | |
0.0375 | 3.25 | 51647 (0.804) | 1092 (0.799) | 2620 (0.804) | 24937 (0.795) | |
8 | 0.0875 | 2.75 | 9272 (0.800) | 178 (0.797) | 781 (0.799) | 12842 (0.801) |
0.1750 | 4.50 | 2509 (0.799) | 70 (0.803) | 297 (0.804) | 3799 (0.799) | |
0.0875 | 6.25 | 10850 (0.797) | 427 (0.797) | 1708 (0.803) | 17768 (0.797) | |
16 | 0.1875 | 4.75 | 2213 (0.797) | 70 (0.793) | 576 (0.797) | 10707 (0.797) |
0.3750 | 8.50 | 647 (0.804) | 34 (0.816) | 233 (0.792) | 3216 (0.803) | |
0.1875 | 12.25 | 3014 (0.803) | 246 (0.798) | 1398 (0.801) | 15240 (0.800) | |
