Table 1 Linkage statistic for thalamus and cortex gray matter volume phenotypes

From: Quantitative trait loci linked to thalamus and cortex gray matter volumes in BXD recombinant inbred mice

Trait

QTL

Proximal

Distal

Chr

Effect size

Effect size/s.d.

LRS

LOD

Proximal (Mb)

Distal (Mb)

P-value

Thalamus volume

D10Mit14

10.114.010

Ms6-3

10

1.932

0.870

10.217

2.22

114.863

119.356

0.0060

 

D11Mit19

11.020.100

D11Mit51

11

2.110

0.951

13.177

2.86

20.849

36.186

0.0013

 

D16mit100

D16Mit9

D16Mit146

16

2.006

0.903

12.101

2.63

6.329

23.570

0.0023

Cortex gray matter

D2Mit42

D2Mit340

D2Mit493

2

12.378

1.097

10.68

2.32

148.315

153.430

0.0048

volume

D8Mit312

08.094.275

D8Mit11

8

12.842

1.138

12.87

2.80

92.292

95.577

0.0016

 

D16Mit100

D16Mit9

D16Mit167

16

12.186

1.080

10.73

2.33

6.329

33.983

0.0046

 

D19Mit40

D19Mit16

D19Mit63

19

13.448

1.192

14.41

3.13

19.593

35.382

0.0007

  1. QTLs that associated with anatomical traits; proximal and distal-markers within a one LOD score drop on the proximal and distal portion of QTL; Chr, the chromosome containing QTL; effect, an estimate of the magnitude of gene. Effect size, the effect size is derived by multiplying the additive effect size by 2. Effect size/s.d., the effect size relative to the amount of variation of each trait; LRS, the likelihood ratio statistic; LOD, logarithm of the odds ratio.
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